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Bachem/(Glu¹⁷·²¹·²⁴)-Osteocalcin (1-49) (human) trifluoroacetate salt/H-7534.0500/0.5 mg
Details
The peptide hormone osteocalcin is involved not only in bone formation, it also plays an important role in glucose metabolism and could regulate testosteron. In mice, only the completely decarboxylated form of the peptide shows the latter hormonal activities, whereas in humans, osteocalcin, partially decarboxylated osteocalcins, and the uncarboxylated peptide seem to be involved. Generally, obese individuals have been shown to have lower osteocalcin(s) levels than non-obese controls, and type 2 diabetic individuals have lower plasma osteocalcin than non-diabetic individuals. Item Number4063516One Letter CodeYLYQWLGAPVPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPVSynonymsOsteocalcin (1-49) (human) (decarboxylated)Molecular FormulaC₂₆₆H₃₈₁N₆₇O₇₆S₂Relative Molecular Mass5797.49CAS Registry Number[1927927-11-4] netSourceSyntheticStorage Conditions-20 ± 5 °CKeywordsBone hormone involved in glucose metabolismAreas of Interest DiabetesObesity Research Links / Documents:
  • Peptide Calculator
  • MSDS
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Product citations
J.Shao et al., Int. J. Endocrinol., 2015, 967673 (2015) L.De Toni et al., Endocrinology, 155, 4266 (2014) A.G.Veldhuis-Vlug et al., Neth. J. Med., 71, 396 (2013) A.R.Guntur and C.J.Rosen, Endocr. Pract., 18, 758 (2012) N.K.Pollock et al., J. Clin. Endocrinol. Metab., 96, E1092 (2011) Y.C.Hwang et al., Diabetes. Metab. Res. Rev, 25, 768 (2009)