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Anti-TNNC2抗体

Anti-TNNC2抗体

产品编号YB-18156R
英文名称TNNC2
中文名称肌钙蛋白C2抗体
别名Fast skeletal muscle troponin C; skeletal muscle; TNNC 2; TNNC2; TNNC2_HUMAN; Troponin C; Troponin C skeletal muscle; Troponin C type 2 (fast); Troponin C type 2; Troponin C2 fast.
规格价格100ul/1380元购买200ul/2200元购买大包装/询价
说明书100ul200ul
研究领域细胞生物免疫学信号转导细胞骨架
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,
产品应用ELISA=1:500-1000IHC-P=1:400-800IHC-F=1:400-800ICC=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
分子量18kDa
细胞定位细胞浆
性状Lyophilized or Liquid
浓度1mg/ml
免疫原KLH conjugated synthetic peptide derived from human TNNC2:2-100/160
亚型IgG
纯化方法affinity purified by Protein A
储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]Function:Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.Similarity:Belongs to the troponin C family.Contains 4 EF-hand domains.SWISS:P02585Gene ID:7125Database links:

Entrez Gene: 7125Human

Entrez Gene: 21925Mouse

Omim: 191039Human

SwissProt: P02585Human

SwissProt: P20801Mouse

Unigene: 182421Human

Unigene: 1716Mouse

Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片Paraformaldehyde-fixed, paraffin embedded (rat liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TNNC2) Polyclonal Antibody, Unconjugated (bs-18156R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining