DescriptionAdditional informationTechnical informationDownloadReferencesRelated productsInformation requestDescriptionIn mouse, the ceacam1 gene exists in two allelic forms, ceacam1a and ceacam1b, and the ceacam1 alleles expressed largely determine mouse susceptibility to MHV. Mouse strains expressing ceacam1a (such as C57BL/6, BALB/c, and C3H) are highly susceptible, while strains homozygous for ceacam1b (such as SJL) are resistant to infection. ceacam1a transcripts are alternatively spliced, yielding four distinct variants in the mouse. These splice variants encode either two or four extracellular immunoglobulin-like (Ig-like) domains linked by a transmembrane domain to a short (10 amino acids) or long (73 amino acids) cytoplasmic tail. The MHV binding site resides within the N-terminal IgV-like domain, D1 . This domain is present in all four isoforms of CEACAM1a, and thus all serve as functional receptors for MHV. Mouse CEACAM1 shares 56% and 70% aa identity with human and rat CEACAM1, respectively. The human and mouse CEACAM1 genes have highly conserved structures, similar patterns of mRNA splicing, and similar patterns of expression in different tissues.Additional informationSize100 µgApplicationClinical diagnostics|Life SciencesProduct typeReagents for researchReagent typeRecombinant proteinCategoryTumor markersSubcategoryCEACAM 1protein fragment. Carcinoembryonic antigen-related cell adhesion molecule 1.Technical informationAccession numberSWS/UNP NP_001034274.1OrganismMouseSize100 µgPotencyBiologically active iestimated by ELISAExpression systemE.coliTagNo taggedPurity>95%FormLiquid, 20mM phosphate buffer pH7.5, 0.5M NaCl, 2mM EDTA, 2mM DTT, 1% sucrose, 10% glycerol.Tested applicationSDS-PAGE, WBShipping/storage conditionsShipped at -20°C. The protein is stable for 12 months if stored at -80°C.Avoid freeze-thaw cycles.UsageFor Laboratory Research Use OnlyDownloadNCBI databaseDatasheet References#tab-title-references{ display: none; }Related productsRecombinant CEACAM 1 PeptideRecombinant CEACAM 1 peptide is 35-143 aa residues of human Carcinoembryonic antigen-related cell adhesion molecule 1(CEACAM1) N-terminal domainproduced in E.coli.REP0054Recombinant CEACAM 1 Protein fragment (Marmoset)The 35-235 residues of marmoset (Callithrix jacchus) CEACAM1 isoform 1 comprising the Nterminal Ig-V like domain, D1 (aa 35-140) and the first Ig-C2 like domain, A1 (aa 146-235) produced in E.coliREP0066Recombinant CEACAM 1 Protein fragment (Human)The 35-235 residues of human CEACAM1 isoform CEACAM1a-4L comprising the N-terminal IgV like domain, D1 (aa 35-140) and the first Ig-C2 like domain, A1 (aa 146-235) produced in E.coliREP0067Information request Name * Last name * Email * Message I give my consent to direct marketing activities, including newsletters, in accordance with the Privacy Policy.I confirm that I have read the Privacy Policy, and I agree to the processing of my personal data..form-1{ font-size:14px; display: inline-block; }.form-1 textarea{ height:80px; }.textwidget input{ width: 155px; }input[type="checkbox"]{ width: 15px !important; }×