- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Description
Calcitonin gene-related peptide II (CGRP II) exhibits vasodilatory and gastrointestinal modulatory activities; it also appears to be associated with inflammation in diseases such as gout and rheumatoid arthritis. CGRP II dilates arterioles in vitro and inhibits pentagastrin-stimulated gastric acid secretion in clinical settings. Like CGRP, this peptide likely binds RAMP1 and CGRP receptors.
Product Info
≥95% |
C163H265N51O50S2 |
3803.39 |
CGRP II, rat; β-CGRP, rat |
Shipping and Storage
-20°C |
Ambient |
Downloads
C0251 Info Sheet PDF |
References
Vanner S. Mechanism of action of capsaicin on submucosal arterioles in the guinea pig ileum. Am J Physiol. 1993 Jul;265(1 Pt 1):G51-5. PMID: 8338172.
Hernanz A, De Miguel E, Romera N, et al. Calcitonin gene-related peptide II, substance P and vasoactive intestinal peptide in plasma and synovial fluid from patients with inflammatory joint disease. Br J Rheumatol. 1993 Jan;32(1):31-5. PMID: 7678534.
Beglinger C, Born W, Hildebrand P, et al. Calcitonin gene-related peptides I and II and calcitonin: distinct effects on gastric acid secretion in humans. Gastroenterology. 1988 Oct;95(4):958-65. PMID: 2900791.
