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Anti-Orexin Receptor 1抗体

Anti-Orexin Receptor 1抗体

产品编号YB-18029R
英文名称Orexin Receptor 1
中文名称丘脑分泌素受体1抗体
别名HCRTR 1; HCRTR1; Hypocretin receptor type 1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1r; OX1R_HUMAN.
规格价格100ul/1380元购买200ul/2200元购买大包装/询价
说明书100ul200ul
研究领域肿瘤细胞生物信号转导G蛋白偶联受体G蛋白信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,
产品应用WB=1:500-2000ELISA=1:500-1000IHC-P=1:400-800IHC-F=1:400-800ICC=1:100-500IF=1:100-500(石蜡切片需做抗原修复)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
分子量48kDa
细胞定位细胞膜
性状Lyophilized or Liquid
浓度1mg/ml
免疫原KLH conjugated synthetic peptide derived from human Orexin Receptor 1:101-200/425
亚型IgG
纯化方法affinity purified by Protein A
储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMedPubMed
产品介绍background:The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]Function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.Subcellular Location:Cell membrane.Similarity:Belongs to the G-protein coupled receptor 1 family.SWISS:O43613Gene ID:3061Database links:

Entrez Gene: 3061Human

Entrez Gene: 230777Mouse

Entrez Gene: 25593Rat

Omim: 602392Human

SwissProt: O43613Human

SwissProt: P58307Mouse

SwissProt: P56718Rat

Unigene: 388226Human

Unigene: 246595Mouse

Unigene: 88262Rat

Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片Sample: A549 Cell (Human) Lysate at 30 ugPrimary: Anti-Orexin Receptor 1 (bs-18029R)at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 48kDObserved band size: 48kD