Enzolifesciences/IDO1 (mouse) monoclonal antibody (mIDO-48)/ALX-804-901-0100/100µg
Product Specification:
| Alternative Name: | INDO, Indoleamine 2,3-dioxygenase, Indole 2,3-dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase |
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| Clone: | mIDO-48 |
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| Host: | Rat |
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| Isotype: | IgG2b |
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| Immunogen: | Recombinant mouse IDO1. |
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| UniProt ID: | P28776 |
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| Gene/Protein Identifier: | 15930 (Entrez GeneID) |
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| Species reactivity: | Mouse |
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| Crossreactivity: | Does not cross-react with IDO2 . |
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| Applications: | WB |
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| Application Notes: | Cited applications include IHC. |
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| Purity Detail: | Affinity purified. |
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| Formulation: | Liquid. In PBS, pH 7.2, containing 0.09% sodium azide. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Scientific Background: | Indoleamine 2,3-dioxygenase (IDO) is an IFN-γ inducible gene. It catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated in protection against intracellular and extracellular pathogens. The mIDO-48 monoclonal antibody recognizes mouse IDO also known as Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, and Indoleamine-pyrrole 2,3-dioxygenase. This antibody does not appear to react with human IDO. IDO is a ubiquitously expressed cytoplasm protein with a predicted molecular weight approximately 45 kDa. Indoleamine 2,3-dioxygenase (IDO) is one the best known IFN-γ inducible genes. The product of IDO gene catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated in protection against intracellular and extracellular pathogens. It also has been shown to maintain the special immune suppressive status of immune-privileged sites such as the brain, eyes, kidney, and placenta. The IDO antibody has been shown to be useful for western blotting and Immunohistochemistry. |
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