Tocris厂家直采，平行进口 TOCRIS 4372-10MG,Tocris/Chaetoglobosin A/5804/1/1 mg,抗生素,细胞培养,细胞相关,,Tocris Bioscience蚂蚁淘商城

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Tocris/Chaetoglobosin A/5804/1/1 mg

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Tocris Bioscience

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5804/1

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4000-520-616

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Description:Antibiotic;selectivelyinducesapoptosisofCLLcells

ChemicalName:(1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-4,7,14,14a,15,15a,16a,16b-Octahydro-7-hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-3H-cyclotridec[d]oxireno[f]isoindole-8,11,12(13H)-trione

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antibiotic;preferentiallyinducesapoptosisinchroniclymphocyticleukemia(CLL)cellsovernormalBcells.InhibitsactinpolymerizationandleadstotheaccumulationofcellsinG₂phase.

TechnicalData

M.Wt	528.64
Formula	C₃₂H₃₆N₂O₅
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	50335-03-0
PubChemID	102601376
InChIKey	OUMWCYMRLMEZJH-ZDSWJECVSA-N
Smiles	[H][C@]12[C@@H](NC([C@]13C(/C=C/C([C@@H](/C(C)=C[C@H](C/C=C/[C@]3([C@@H]4O[C@@]4([C@H]2C)C)[H])C)O)=O)=O)=O)CC5=CNC6=C5C=CC=C6

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	52.86	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight528.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.89mL	9.46mL	18.92mL
5mM	0.38mL	1.89mL	3.78mL
10mM	0.19mL	0.95mL	1.89mL
50mM	0.04mL	0.19mL	0.38mL

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