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Tocris/Filipin III/6250/1/1 mg

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Tocris Bioscience

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6250/1

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4000-520-616

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Description:Polyeneantibiotic;inhibitsformationofpathologicalisoformofprionprotein

ChemicalName:(3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-Octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Polyeneantibiotic.Bindssterolsinfungalmembranes.Alsoinhibitsformationofthepathologicalformofprionprotein(PrP-res)fromthenormalmembrane-bound(PrP-sen)form.Alsofluorescentcholesterolstain.

TechnicalData

M.Wt	654.83
Formula	C₃₅H₅₈O₁₁
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	480-49-9
PubChemID	6433553
InChIKey	IMQSIXYSKPIGPD-ZPXVTHDFSA-N
Smiles	C[C@@H](O1)[C@@H](O)/C=C/C=C/C=C/C=C/C=C(C)/[C@@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)C[C@H](O)[C@]([C@H](O)CCCCC)([H])C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	3.27	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight654.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.53mL	7.64mL	15.27mL
5mM	0.31mL	1.53mL	3.05mL
10mM	0.15mL	0.76mL	1.53mL
50mM	0.03mL	0.15mL	0.31mL

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