BiologicalActivity
Highaffinitycaveolin-1(CAV1)ligand(Kd=23nM);disruptscaveolin-1oligomers.ExhibitsselectivityforCAV1overBSA,caseinandHEWL.
LicensingInformation
SoldwithkindpermissionofProfessorGregoryWeiss
TechnicalData
| M.Wt | 1844.3 |
| Formula | C80H130N24O18S4 |
| Sequence | CSWMRLKCSWMRLK* (Modifications:DisulfideBridge=1-1*) |
| Storage | Storeat-20°C |
| PubChemID | 123773278 |
| InChIKey | DNQUEMNLAOMZEO-HFXGPFCTSA-N |
| Smiles | [H]N[C@@H](CSSC[C@H](N[H])C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1844.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.54mL | 2.71mL | 5.42mL |
| 5mM | 0.11mL | 0.54mL | 1.08mL |
| 10mM | 0.05mL | 0.27mL | 0.54mL |
| 50mM | 0.01mL | 0.05mL | 0.11mL |
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