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Tocris/TA 01/5383/10/10 mg
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Description:InducescardiomyocytedifferentiationfromhESCs
ChemicalName:4-(2-(2,6-Difluorophenyl)-4-(fluorophenyl)-1H-imidazol-5-yl)pyridine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inducescardiomyocytedifferentiationfromhumanembryonicstemcellsfollowingmesoderminductionat1μM.Inhibitscardiomyocytedifferentiationat5μM.PotentlyinhibitsCK1ε,p38α,andCK1δ(IC50valuesare6.4,6.7and6.8nMrespectively).
LicensingInformation
SoldunderagreementfromtheAgencyforScience,TechnologyandResearch(A*STAR),ETPL,andaffiliatesincludingtheBioprocessingTechnologyInstitute.
TechnicalData
M.Wt | 351.32 |
Formula | C20H12F3N3 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
PubChemID | 91691129 |
InChIKey | TWPJJJZCYVFUOA-UHFFFAOYSA-N |
Smiles | FC(C=C4)=CC=C4C(N=C(C3=C(F)C=CC=C3F)N2)=C2C1=CC=NC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 35.13 | 100 | |
ethanol | 3.51 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight351.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.85mL | 14.23mL | 28.46mL |
5mM | 0.57mL | 2.85mL | 5.69mL |
10mM | 0.28mL | 1.42mL | 2.85mL |
50mM | 0.06mL | 0.28mL | 0.57mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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