Overview:
Valproic acid analog. Histone deacetylase (HDAC) inhibitor, IC50=13 uM1.More potent and robust than valproic acid at inducing histone hyperacetylation (600% at 50 mM), HSP70 induction and protection against glutamate excitotoxicity in cultured neurons2. Cell permeable.
References:
1. D Eikel et al. Chem. Res. Toxicol.2006 19:2722. Y Leng et al. Neurosci. Lett.2010 476:127
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如图,方法是默克给的厂家标准,样品为叔丁醇
现在想把KOH滴定液换成NaOH滴定液,但是领导死活让找依据不然就要做验证
我想知道有没有哪位大神知道这个方法的具体出处。
最好权威一点
暂无品牌问答