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Tocris/Ro 90-7501/2408/10/10 mg
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Description:InhibitorofAβ42fibrilformation
ChemicalName:2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inhibitorofamyloidβ42(Aβ42)fibrilassembly;reducesAβ42-inducedtoxicity(EC50=2μM).
CompoundLibraries
Ro90-7501isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 340.39 |
Formula | C20H16N6 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 293762-45-5 |
PubChemID | 824226 |
InChIKey | PAGZCEHLFCJSPV-UHFFFAOYSA-N |
Smiles | NC1=CC=C(C=C1)C1=NC2=CC=C(C=C2N1)C1=NC2=CC=C(N)C=C2N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
1eq.HCl | 3.4 | 10 | |
DMSO | 34.04 | 100 | |
ethanol | 34.04 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight340.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.94mL | 14.69mL | 29.38mL |
5mM | 0.59mL | 2.94mL | 5.88mL |
10mM | 0.29mL | 1.47mL | 2.94mL |
50mM | 0.06mL | 0.29mL | 0.59mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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