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Tocris/TRC 051384/4734/10/10 mg
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Description:InducerofheatshockproteinHsp70
ChemicalName:N-[2-(4-Morpholinyl)ethyl]-N'-[4-[3-[6-(4-morpholinyl)-2-pyridinyl]-1-oxo-2-propen-1-yl]phenyl]urea
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
InducerofheatshockproteinHsp70;reducesstroke-associatedneuronalinjuryandincreasessurvivalinaratmodeloftransientischemicstroke.Activatesheatshockfactor-1andresultsinelevatedchaperoneandanti-inflammatoryactivity.EnhancesHsp72expressioninneuronsandglialcells.
TechnicalData
M.Wt | 465.54 |
Formula | C25H31N5O4 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 867164-40-7 |
PubChemID | 11634093 |
InChIKey | SQTSPANZQDCPLB-CMDGGOBGSA-N |
Smiles | O=C(C3=CC=C(NC(NCCN4CCOCC4)=O)C=C3)/C=C/C1=CC=CC(N2CCOCC2)=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 53.85 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight465.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.15mL | 10.74mL | 21.48mL |
5mM | 0.43mL | 2.15mL | 4.3mL |
10mM | 0.21mL | 1.07mL | 2.15mL |
50mM | 0.04mL | 0.21mL | 0.43mL |
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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