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Tocris/Cytochalasin B/5474/10/10 mg
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Tocris/Cytochalasin B/5474/10/10 mg
品牌 / 
Tocris Bioscience
货号 / 
5474/10
美元价:
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数    量:
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4000-520-616
Description:Inhibitorofactinpolymerization
ChemicalName:(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofactinpolymerization.Inhibitscelldivision,migrationandglucosetransport.CausesG2/McellcyclearrestandapoptosisinHCT-116colorectalcarcinomacells.Cellpermeable.

TechnicalData

M.Wt479.61
FormulaC29H37NO5
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber14930-96-2
PubChemID5311281
InChIKeyGBOGMAARMMDZGR-TYHYBEHESA-N
SmilesC=C([C@H]1C)[C@@H](O)[C@]([C@@]2(O3)[C@]1([H])[C@H](CC4=CC=CC=C4)NC2=O)([H])/C=C/C[C@H](C)CCC[C@@H](O)/C=C/C3=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.810mMwithgentlewarming
ethanol9.5920

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight479.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.09mL10.43mL20.85mL
5mM0.42mL2.09mL4.17mL
10mM0.21mL1.04mL2.09mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet