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Tocris/SMIFH2/4401/50/50 mg
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Tocris/SMIFH2/4401/50/50 mg
品牌 / 
Tocris Bioscience
货号 / 
4401/50
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4000-520-616
Description:FH2domaininhibitor;preventsactinnucleation
ChemicalName:1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofforminhomology2(FH2)domains.Preventsformin-mediatedactinnucleationandbarbedendelongation.Disruptsformin-dependentactincytoskeletalstructuresinfissionyeastandmammalianNIH3T3fibroblasts.

TechnicalData

M.Wt377.21
FormulaC15H9BrN2O3S
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber340316-62-3
PubChemID2258538
InChIKeyMVFJHEQDISFYIS-XYOKQWHBSA-N
SmilesO=C(/C(C(N2)=O)=C/C1=CC=CO1)N(C3=CC=CC(Br)=C3)C2=S

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.72100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight377.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.65mL13.26mL26.51mL
5mM0.53mL2.65mL5.3mL
10mM0.27mL1.33mL2.65mL
50mM0.05mL0.27mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet