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Tocris/Anagrelide hydrochloride/2432/50/50 mg
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4000-520-616
Description:PotentPDE3inhibitor
AlternativeNames:BL4162A
ChemicalName:6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-onehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotenttypeIIIphosphodiesterase(PDE3)inhibitor(IC50=36nM).Inhibitsplateletaggregationandproducespotentthrombocytopeniceffectsviainhibitionofmegakaryocytematuration.
TechnicalData
M.Wt | 292.55 |
Formula | C10H7Cl2N3O.HCl |
Storage | Desiccateat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 58579-51-4 |
PubChemID | 42786 |
InChIKey | TVWRQCIPWUCNMI-UHFFFAOYSA-N |
Smiles | ClC1=C(CN(C3)C(N2)=NC3=O)C2=CC=C1Cl.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 2.93 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight292.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.42mL | 17.09mL | 34.18mL |
5mM | 0.68mL | 3.42mL | 6.84mL |
10mM | 0.34mL | 1.71mL | 3.42mL |
50mM | 0.07mL | 0.34mL | 0.68mL |
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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