BiologicalActivity
Proteinsynthesisinhibitor(blockstranslation).Potentactivatorofstress-activatedproteinkinases(JNK/SAPK)andp38MAPkinase.ActsasapotentsignalingagoNISTtoselectivelyelicithomologousdesensitizationofimmediateearlygeneinduction(c-fos,fosB,c-jun,junBandjunD).
TechnicalData
| M.Wt | 265.31 |
| Formula | C14H19NO4 |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 22862-76-6 |
| PubChemID | 253602 |
| InChIKey | YKJYKKNCCRKFSL-RDBSUJKOSA-N |
| Smiles | O[C@H]1CN[C@H](CC2=CC=C(OC)C=C2)[C@@H]1OC(C)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.53 | 100 | |
| ethanol | 13.27 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight265.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.77mL | 18.85mL | 37.69mL |
| 5mM | 0.75mL | 3.77mL | 7.54mL |
| 10mM | 0.38mL | 1.88mL | 3.77mL |
| 50mM | 0.08mL | 0.38mL | 0.75mL |
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