BiologicalActivity
CaMkinaseIIinhibitor;enhancedcellpermeablederivativeofAutocamtide-2-relatedinhibitorypeptide(CatNo.1688).Pretreatmentblocksreinstatementofmorphine-seekingbehaviorinvivo.
TechnicalData
| M.Wt | 1708.12 |
| Formula | C78H142N22O20 |
| Sequence | KKALRRQEAVDAL (Modifications:Lys-1=Myr-Lys) |
| Storage | Storeat-20°C |
| CASNumber | 201422-04-0 |
| PubChemID | 121513908 |
| InChIKey | QKOOKZWMKXOQRL-YJDHHEDVSA-N |
| Smiles | [H]N[C@@H](CCCCNC(=O)CCCCCCCCCCCCC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1708.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.59mL | 2.93mL | 5.85mL |
| 5mM | 0.12mL | 0.59mL | 1.17mL |
| 10mM | 0.06mL | 0.29mL | 0.59mL |
| 50mM | 0.01mL | 0.06mL | 0.12mL |
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