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Tocris/MitoPY1/4428/10/10 mg

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Tocris Bioscience

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4428/10

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Description:Fluorescentmitochondrialhydrogenperoxideindicator

ChemicalName:[4-[4-[3-Oxo-6'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl]-1-piperazinyl]butyl]triphenyl-phosphoniumiodide

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Fluorescentprobeforimaginghydrogenperoxide(H₂O₂)inmitochondriaoflivingcells.Displaysenhancedemissionat528nminthepresenceofH₂O₂.SelectiveforH₂O₂oversuperoxide,nitricoxideandhydroxylrADIcal.DetectslocalincreasesinH₂O₂inaninvitromodelofParkinson'sDisease.

LicensingInformation

SoldunderlicensefromtheRegentsoftheUniversityofCalifornia

TechnicalData

M.Wt	954.68
Formula	C₅₂H₅₃BIN₂O₅P
Storage	Storeat-20°C
CASNumber	1041634-69-8
PubChemID	90488942
InChIKey	JPCCULDYUUMFAD-UHFFFAOYSA-M
Smiles	O=C(O4)C5=C(C=CC=C5)C24C1=CC=C(N6CCN(CCCC[P+](C9=CC=CC=C9)(C%10=CC=CC=C%10)C8=CC=CC=C8)CC6)C=C1OC3=C2C=CC(B7OC(C)(C)C(C)(C)O7)=C3.[I-]

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	95.47	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight954.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.05mL	5.24mL	10.47mL
5mM	0.21mL	1.05mL	2.09mL
10mM	0.1mL	0.52mL	1.05mL
50mM	0.02mL	0.1mL	0.21mL

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