ISOTYPE: Mouse IgG1k
INFORMATION: The p75 low affinity human Nerve Growth Factor receptor CD271(NGRF, TNFRSF16) is expressed on a variety of tissue types including a subset of splenic and nodal lymphocytes. Presence of this receptor supports uptake of intracellular calcium, but not mobilization (3). CD271 is a stem cell marker for hematopoietic(5,6,7), stromal (8) as well as cancer cells (9,10). CD271 has been reported to inhibit differentiation of mesenchymal cells into various lineages(11).
Antibody ANC271/3D7 binds to recombinant CD271-muIg (cat# 527-020) in EIA, and to endogenous CD271 on cell surface of human Reh cells.
REFERENCES:
1) Brodie C, E W Gelfand (1992) Journal of Immunology. 148(11): 3492-3497.
2) Fantini F, O. Johansson (1992) Journal of Investigative Dermatology. 99(6): 734-742.
3) Jiang H, G Gurogg, et al.(1999) J Biol Chem 274(37): 26209-16.
4) Khwaja F, D Djakiew, et al (2004) Cancer Res 64(17): 6207-13.
5) Flores-Torales E, Cuneo-Pareto S, et al. (2010) Folia Histochem Cytobiol. 48(4):682-6.
6) Kuçi S, Bader P, et al. (2010) Haematologica. 95(4):651-9.
7) Hermida-Gómez T, Blanco FJ, et al. (2011) Tissue Eng Part A. 17(7-8):1169-79.
8) Jones E, McGonagle D, et al. (2010) Arthritis Rheum. 62(7):1944-54.
9) Boiko AD, Weissman IL. Et al. (2010) Nature 466(7302):133-7.
10) Civenni G, Sommer L, et al. (2011) Cancer Res. 71(8):3098-109.
11) Mikami Y, Honda MJ, et al. (2011) Stem Cells Dev. 20(5):901-13.
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如果需要储液箱，那储液箱和微型定量泵之间用什么连接？是用管道吗？
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