HTI (Haemaologic Technologies)发色底物优势订购，量大优惠，_蚂蚁淘，【正品极速】生物医学科研用品轻松购|ebiomall -蚂蚁淘商城

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HTI (Haemaologic Technologies)发色底物优势订购，量大优惠，

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HaematologicTechnologiesInc(HTI)公司是一家专门致力于高质量的人血浆蛋白的分离和特性研究的重要生产商，其产品非常适用于体内研究。在公司发展的第二个十年里，HTI将目光投向参与血液凝集和纤维蛋白溶解，以及骨代谢调节的蛋白的研究。HTI产品系列含有超过100种高纯度和特异性的蛋白，包括：酶原、酶、协同因子和抑制剂，同时还提供补体系列的单克隆和多克隆抗体。另外，HTI还提供一些技术服务，如：蛋白定制、纯化、修饰、科研合作等

Alpha-thrombinisaserineproteaseandakeyenzymeinthebloodcoagulation
woundhealingprocesses.Thrombinisgeneratedbyproteolyticactivationofthe
zymogenprothrombinandiscommonlyrecognizedastheenzymeresponsIBLefo
theconversionoffibrinogentofibrin.Inadditiontocleavingfibrinogen,thrombin
isresponsibleforactivatingplateletsandisindirectlyresponsibleforregulation
itsownproductionandinhibitionthroughmultipleproteolyticfeedbackpathway
whichincludetheactivationoffactorsV,VIII,XIandProteinC.Thecentral
importanceofthrombintotheoverallcoagulationprocessisestablishedbythe
factthatanyperturbationwithinthebloodcoagulationsystemthatresultsin
significantlyamplifiedorimpairedaswellasacceleratedordelayedthrombin
generationwillresultinclinicallyrelevanthemorrhagicorthromboticevents.
Thrombinactivityisdown-regulatedbyinactivationofthecofactors,factorVaa
VIIIaorbydirectinhibitionofthrombinbyitsprincipalinhibitor,anti-thrombin-III
Inadditiontoitspivitolroleinthebloodcoagulationprocess,thrombinalso
contributestothewoundhealingprocess.Itactivatesproteaseactivated
receptor-1(PAR-1)andinthismannercanaffectcellularfunction,growthand
proliferation.Intactthrombin,aswellasfragmentsofthrombin,havealsobeen
showntohaveangiogenic,mitogenicandchemotacticactivities.