BiologicalActivity
NAADPinhibitor.PreventsCa2+oscillationsinratcardiomyocytesinvitroduringsimulatedischemiaandreperfusion,butexhibitsnosignificanteffectonCa2+sparks.Significantlyreducesinfarctsizeinratcardiacischemia/reperfusionmodelinvivo.
TechnicalData
| M.Wt | 521.61 |
| Formula | C31H31N5O3 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| PubChemID | 127021041 |
| InChIKey | LMTWTJMBOFXQTH-LITSAYRRSA-N |
| Smiles | O=C(O)[C@H]1N[C@H](C2=CC=C(OC)C(CN3CCN(C4=CC=CC=C4C#N)CC3)=C2)C5=C(C(C=CC=C6)=C6N5)C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 26.08 | 50 | |
| ethanol | 10.43 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight521.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.92mL | 9.59mL | 19.17mL |
| 5mM | 0.38mL | 1.92mL | 3.83mL |
| 10mM | 0.19mL | 0.96mL | 1.92mL |
| 50mM | 0.04mL | 0.19mL | 0.38mL |
MolarityCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
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