BiologicalActivity
InhibitorofCav3.2channels(IC50=6.5μM);displaysnoeffectonCav3.1orCav3.3channelsheterologouslyexpressedinHEK293cells.Alsoenhancesthegenerationofinducedpluripotentstemcells(iPSCs)frommouseandhumansomaticcellsbyincreasingreprogrammingefficiency.Naturallyoccurringantioxidant.
CompoundLibraries
L-AscorbicacidisalsoofferedaspartoftheTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 176.12 |
| Formula | C6H8O6 |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 50-81-7 |
| PubChemID | 54670067 |
| InChIKey | CIWBSHSKHKDKBQ-JLAZNSOCSA-N |
| Smiles | OC1=C(O)[C@]([C@@H](O)CO)([H])OC1=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 17.61 | 100 | |
| water | 88.06 | 500 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight176.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.68mL | 28.39mL | 56.78mL |
| 5mM | 1.14mL | 5.68mL | 11.36mL |
| 10mM | 0.57mL | 2.84mL | 5.68mL |
| 50mM | 0.11mL | 0.57mL | 1.14mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
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