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Tocris/B2/2855/50/50 mg

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Tocris Bioscience

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2855/50

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Description:PromotesinclusionformationinHuntington'sandParkinson'sdiseases

AlternativeNames:CPNQ

ChemicalName:5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PromotesinclusionformationincellularmodelsofHuntington'sdiseaseandParkinson'sdisease.Preventsmutanthuntingtin-mediatedproteasomedysfunctionandreducesα-synuclein-mediatedtoxicity.

TechnicalData

M.Wt	396.83
Formula	C₂₀H₁₇ClN₄O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	115687-05-3
PubChemID	3953303
InChIKey	KLNPVNZJCWIQSK-UHFFFAOYSA-N
Smiles	O=C(C4=CC=C(Cl)C=C4)N(CC3)CCN3C1=C(C=CC=N2)C2=C([N+]([O-])=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	39.68	100
	ethanol	3.97	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight396.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.52mL	12.6mL	25.2mL
5mM	0.5mL	2.52mL	5.04mL
10mM	0.25mL	1.26mL	2.52mL
50mM	0.05mL	0.25mL	0.5mL

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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