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Tocris/BAM 15/5737/10/10 mg
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Description:Mitochondrialprotonophoreuncoupler
ChemicalName:N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxADIazolo[3,4-b]pyrazine-5,6-diamine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Mitochondrialprotonophoreuncoupler;uncouplesoxidativephosphorylationinL6myoblastmitochondriainvitro(EC50=270nM).Doesnotdepolarizetheplasmamembrane.Protectsmicefromacuterenalischemic-reperfusioninjury.
TechnicalData
M.Wt | 340.29 |
Formula | C16H10F2N6O |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 210302-17-3 |
PubChemID | 565708 |
InChIKey | OEGJBRZAJRPPHL-UHFFFAOYSA-N |
Smiles | FC1=C(C=CC=C1)NC2=NC3=NON=C3N=C2NC4=C(C=CC=C4)F |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 34.03 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight340.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.94mL | 14.69mL | 29.39mL |
5mM | 0.59mL | 2.94mL | 5.88mL |
10mM | 0.29mL | 1.47mL | 2.94mL |
50mM | 0.06mL | 0.29mL | 0.59mL |
MolarityCalculator
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Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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