进口Tocris品牌清关代理 Tocris化合物筛选文库,Tocris/BAM 7/4810/10/10 mg,其他试剂,其他,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/BAM 7/4810/10/10 mg

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Tocris Bioscience

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4810/10

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4000-520-616

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Description:SelectiveBaxactivator;inducesBax-mediatedapoptosis

ChemicalName:3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione4-[2-(2-Ethoxyphenyl)hydrazone]

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Baxactivator(EC₅₀=3.3μM);bindsattheBH3-bindingsite.SelectiveforBaxoverotherantiapoptoticandproapoptoticproteins.TriggersBaxoligomerizationinvitro;inducesBax-mediatedapoptosisinmouseembryonicfibroblasts.

TechnicalData

M.Wt	405.47
Formula	C₂₁H₁₉N₅O₂S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	331244-89-4
PubChemID	5754137
InChIKey	KOCVKGYKBLJEPK-LYBHJNIJSA-N
Smiles	CC(/C1=NNC2=C(OCC)C=CC=C2)=NN(C3=NC(C4=CC=CC=C4)=CS3)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	4.05	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight405.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.47mL	12.33mL	24.66mL
5mM	0.49mL	2.47mL	4.93mL
10mM	0.25mL	1.23mL	2.47mL
50mM	0.05mL	0.25mL	0.49mL

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