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Tocris/cis-6-Hydroxynorketamine hydrochloride/5982/50/50 mg
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4000-520-616
Description:EnhancesAMPAcurrents:antidepressant
ChemicalName:cis-2-Amino-2-(2-chlorophenyl)-6-hydroxycyclohexanonehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Metaboliteofketamine(Cat.No.3131).IncreasesAMPAreceptor-mediatedexcitatorypost-synapticpotentialsintheCA1regionofhippocampalslices.Exhibitsantidepressiveeffectsinvivo.2S,2S-and2R,6R-enantiomersavailable.2R,6R-enantiomerlacksketamine-relatedsideeffects.
TechnicalData
M.Wt | 276.16 |
Formula | C12H14ClNO2.HCl |
Storage | DesiccateatRT |
Purity | ≥98%(HPLC) |
PubChemID | 121513910 |
InChIKey | ZQJVHBJDLMIKJK-MHDYBILJSA-N |
Smiles | ClC1=C([C@@]2(N)C([C@H](O)CCC2)=O)C=CC=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 27.62 | 100 | |
water | 27.62 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight276.16.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.62mL | 18.11mL | 36.21mL |
5mM | 0.72mL | 3.62mL | 7.24mL |
10mM | 0.36mL | 1.81mL | 3.62mL |
50mM | 0.07mL | 0.36mL | 0.72mL |
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ReconstitutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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