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Tocris/MMF/4511/50/50 mg
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4000-520-616
Description:ActivatorofNrf2pathway;primarymetaboliteofDMF(Cat.No.4512)
AlternativeNames:mono-Methylfumarate
ChemicalName:2(E)-Butenedioicacid1-methylester
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Nuclearfactor(erythroid-derived-2)-like2(Nrf2)pathwayactivator.AlsoexhibitsagoNISTactivityatGPR109A.PrimarymetaboliteofDMF(Cat.No.4512).
TechnicalData
M.Wt | 130.1 |
Formula | C5H6O4 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 2756-87-8 |
PubChemID | 5369209 |
InChIKey | NKHAVTQWNUWKEO-NSCUHMNNSA-N |
Smiles | O=C(/C=C/C(O)=O)OC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 13.01 | 100 | |
ethanol | 13.01 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight130.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 7.69mL | 38.43mL | 76.86mL |
5mM | 1.54mL | 7.69mL | 15.37mL |
10mM | 0.77mL | 3.84mL | 7.69mL |
50mM | 0.15mL | 0.77mL | 1.54mL |
MolarityCalculator
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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