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Tocris/O4I2/5664/10/10 mg
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Tocris/O4I2/5664/10/10 mg
品牌 / 
Tocris Bioscience
货号 / 
5664/10
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4000-520-616
Description:Oct3/4inducer;inducesexpressionofpluripotent-associatedgenes
ChemicalName:Ethyl2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Oct3/4inducer;promotesOct3/4expressionandstABIlizestheOct3/4proteininHEK293cells.Inducesexpressionofpluripotent-associatedgenesLin28,Sox2andNanog,andsuppressesRex1.Induces15-foldincreaseinOct3/4expressioninhumanprimaryfibroblasts.

CompoundLibraries

O4I2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt282.75
FormulaC12H11ClN2O2S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber165682-93-9
PubChemID53428670
InChIKeyULUBAPWNHROTEU-UHFFFAOYSA-N
SmilesClC(C=C2)=CC=C2NC1=NC(C(OCC)=O)=CS1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.27100
ethanol14.1450

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight282.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.54mL17.68mL35.37mL
5mM0.71mL3.54mL7.07mL
10mM0.35mL1.77mL3.54mL
50mM0.07mL0.35mL0.71mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet