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Tocris/O4I2/5664/10/10 mg
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4000-520-616
Description:Oct3/4inducer;inducesexpressionofpluripotent-associatedgenes
ChemicalName:Ethyl2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Oct3/4inducer;promotesOct3/4expressionandstABIlizestheOct3/4proteininHEK293cells.Inducesexpressionofpluripotent-associatedgenesLin28,Sox2andNanog,andsuppressesRex1.Induces15-foldincreaseinOct3/4expressioninhumanprimaryfibroblasts.
CompoundLibraries
O4I2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 282.75 |
Formula | C12H11ClN2O2S |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 165682-93-9 |
PubChemID | 53428670 |
InChIKey | ULUBAPWNHROTEU-UHFFFAOYSA-N |
Smiles | ClC(C=C2)=CC=C2NC1=NC(C(OCC)=O)=CS1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 28.27 | 100 | |
ethanol | 14.14 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight282.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.54mL | 17.68mL | 35.37mL |
5mM | 0.71mL | 3.54mL | 7.07mL |
10mM | 0.35mL | 1.77mL | 3.54mL |
50mM | 0.07mL | 0.35mL | 0.71mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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