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Tocris/OGT 2115/2710/1/1 mg
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4000-520-616
Description:Antiangiogenic.Heparanaseinhibitor
ChemicalName:2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleaceticacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Heparanaseinhibitor(IC50=0.4μM)thatdisplaysnomajorinhibitionofhumancytochromeP450isoenzymes(IC50>30μM).Exhibitsantiangiogenicpropertiesinvitro(IC50=1μM).
TechnicalData
M.Wt | 495.3 |
Formula | C24H16BrFN2O4 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 853929-59-6 |
PubChemID | 44402523 |
InChIKey | LKBXWNYXDMSFQU-ONNFQVAWSA-N |
Smiles | O=C(/C=C/C4=CC=C(Br)C=C4)NC(C(F)=C3)=CC=C3C2=NC1=CC(CC(O)=O)=CC=C1O2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 4.95 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight495.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.02mL | 10.09mL | 20.19mL |
5mM | 0.4mL | 2.02mL | 4.04mL |
10mM | 0.2mL | 1.01mL | 2.02mL |
50mM | 0.04mL | 0.2mL | 0.4mL |
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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