BiologicalActivity
Ruthenium-bipyridine-trimethylphosphinecagedglutamatethatcanbeexcitedbyvisiblewavelengthsandreleasesglutamateafterone-ortwo-photonexcitation.Hashighquantumefficiencyandcanbeusedatlowconcentrations,partlyavoidingblockadeofGABAergictransmissionseenwithothercagedglutamatecompounds.Displayshighspatialresolutionandgeneratesexcitatoryresponsesinindividualdendriticspineswithphysiologicalkinetics.
LicensingInformation
SoldunderlicencefromColumbiaUniversity
TechnicalData
| M.Wt | 970.54 |
| Formula | C28H32N5O4PRu.2NaPF6 |
| Storage | Storeat-20°C |
| PubChemID | 90488860 |
| InChIKey | SQQVSHWHIPVYSZ-UHFFFAOYSA-L |
| Smiles | [Na+].[Na+].[Ru++].CP(C)C.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.NC(CCC([O-])=O)C([O-])=O.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CN=C(C=C1)C1=CC=CC=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 16.07 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight970.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.03mL | 5.15mL | 10.3mL |
| 5mM | 0.21mL | 1.03mL | 2.06mL |
| 10mM | 0.1mL | 0.52mL | 1.03mL |
| 50mM | 0.02mL | 0.1mL | 0.21mL |
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