BiologicalActivity
Greatlyenhancestheefficiencyoffibroblastreprogrammingtogenerateinducedpluripotentstemcells(iPSCs)whenusedincombinationwithSB431542(Cat.No.1614)andPD0325901(Cat.No.4192).Improvesthesurvivalofhumanembryonicstemcells(hESCs)upontrypsinization.
CompoundLibraries
ThiazovivinisalsoofferedaspartoftheTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 311.36 |
| Formula | C15H13N5OS |
| Storage | Storeat-20°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 1226056-71-8 |
| PubChemID | 46209426 |
| InChIKey | DOBKQCZBPPCLEG-UHFFFAOYSA-N |
| Smiles | O=C(NCC3=CC=CC=C3)C1=CSC(NC2=CC=NC=N2)=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.14 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight311.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.21mL | 16.06mL | 32.12mL |
| 5mM | 0.64mL | 3.21mL | 6.42mL |
| 10mM | 0.32mL | 1.61mL | 3.21mL |
| 50mM | 0.06mL | 0.32mL | 0.64mL |
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