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Tocris/AS 1269574/4177/50/50 mg
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Tocris/AS 1269574/4177/50/50 mg
品牌 / 
Tocris Bioscience
货号 / 
4177/50
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4000-520-616
Description:GPR119receptoragoNIST
ChemicalName:2-[[2-(4-Bromophenyl)-6-methyl-4-pyrimidinyl]amino]ethanol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPR119receptoragonist(EC50=2.5μMinHEK293cellsexpressinghumanGPR119).Enhancesinsulinsecretionstimulatedbyglucoseinvivo.Stimulatesproglucagongenepromoteractvity.Orallyavailable.

CompoundLibraries

AS1269574isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt308.17
FormulaC13H14BrN3O
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber330981-72-1
PubChemID5332859
InChIKeyDUKPGOOUJNUIOI-UHFFFAOYSA-N
SmilesBrC(C=C2)=CC=C2C1=NC(NCCO)=CC(C)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.82100
ethanol30.82100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight308.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.24mL16.22mL32.45mL
5mM0.65mL3.24mL6.49mL
10mM0.32mL1.62mL3.24mL
50mM0.06mL0.32mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet