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Tocris/AS 8351/6044/10/10 mg
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Description:Inducesreprogrammingoffibroblastsintofunctionalcardiomyocytes
ChemicalName:2-Hydroxy-1-naphthaldehydeisonicotinoylhydrazone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inducesreprogrammingofhumanfetallungfibroblastsintofunctionalcardiomyocytes,incombinationwithCHIR99021,A83-01,BIX01294,SC1,Y-27632,OAC2,SU16fandJNJ10198409.IronchelatorandputativeinhibitorofKDM5B.
TechnicalData
M.Wt | 291.3 |
Formula | C17H13N3O2 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 796-42-9 |
PubChemID | 5353827 |
InChIKey | UBECDIQQXGETMR-PTNGSMBKSA-N |
Smiles | OC1=C(C2=CC=CC=C2C=C1)/C=N/NC(C3=CC=NC=C3)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 29.13 | 100 | |
ethanol | 1.46 | 5mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight291.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.43mL | 17.16mL | 34.33mL |
5mM | 0.69mL | 3.43mL | 6.87mL |
10mM | 0.34mL | 1.72mL | 3.43mL |
50mM | 0.07mL | 0.34mL | 0.69mL |
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ReconstitutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
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