BiologicalActivity
Inducesreprogrammingofhumanfetallungfibroblastsintofunctionalcardiomyocytes,incombinationwithCHIR99021,A83-01,BIX01294,SC1,Y-27632,OAC2,SU16fandJNJ10198409.IronchelatorandputativeinhibitorofKDM5B.
TechnicalData
| M.Wt | 291.3 |
| Formula | C17H13N3O2 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 796-42-9 |
| PubChemID | 5353827 |
| InChIKey | UBECDIQQXGETMR-PTNGSMBKSA-N |
| Smiles | OC1=C(C2=CC=CC=C2C=C1)/C=N/NC(C3=CC=NC=C3)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.13 | 100 | |
| ethanol | 1.46 | 5mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight291.3.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.43mL | 17.16mL | 34.33mL |
| 5mM | 0.69mL | 3.43mL | 6.87mL |
| 10mM | 0.34mL | 1.72mL | 3.43mL |
| 50mM | 0.07mL | 0.34mL | 0.69mL |
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