BiologicalActivity
Highaffinityadeninereceptoragonist(Ki=18nMatratadeninereceptor).Inhibitsforskolin-stimulatedcAMPformationinCHOcellstransfectedwiththeadeninereceptor;alsostimulatesGTPγSbinding(pEC50valuesare8.54and7.21respectively).
TechnicalData
| M.Wt | 171.59 |
| Formula | C5H5N5.HCl |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 6055-72-7 |
| PubChemID | 76219 |
| InChIKey | UQVDQSWZQXDUJB-UHFFFAOYSA-N |
| Smiles | NC1=C2C(NC=N2)=NC=N1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 17.16 | 100 | |
| water | 17.16 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight171.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.83mL | 29.14mL | 58.28mL |
| 5mM | 1.17mL | 5.83mL | 11.66mL |
| 10mM | 0.58mL | 2.91mL | 5.83mL |
| 50mM | 0.12mL | 0.58mL | 1.17mL |
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