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Tocris/Altanserin hydrochloride/1809/10/10 mg
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Tocris/Altanserin hydrochloride/1809/10/10 mg
品牌 / 
Tocris Bioscience
货号 / 
1809/10
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4000-520-616
Description:5-HT2AreceptorantagoNIST
ChemicalName:3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinonehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselective5-HT2Areceptorantagonist(Kivaluesare0.13,4.55,40,62and1570nMat5-HT2A,α1,5-HT2C,D2and5-HT1Arespectively).Centrallyactivefollowingsystemicadministrationinvivo.

CompoundLibraries

AltanserinhydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt447.95
FormulaC22H22FN3O2S.HCl
StorageDesiccateat+4°C
Purity≥98%(HPLC)
CASNumber1135280-78-2
PubChemID24978536
InChIKeyJFPPLMAMMZZOEA-UHFFFAOYSA-N
SmilesCl.FC1=CC=C(C=C1)C(=O)C1CCN(CCN2C(=S)NC3=CC=CC=C3C2=O)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.9620mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight447.95.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.23mL11.16mL22.32mL
5mM0.45mL2.23mL4.46mL
10mM0.22mL1.12mL2.23mL
50mM0.04mL0.22mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet