BiologicalActivity
HighlyselectiveH2agonist,slightlymorepotentthanhistamineitself.OnlyaweakantagonistatH3andhasnoactivityatH1receptors.Inducesvasodilationofcerebralarteriesanddecreasesmyogenictoneinvitro.
TechnicalData
| M.Wt | 319.06 |
| Formula | C6H11N3S.2HBr |
| Storage | Desiccateat-20°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 142457-00-9 |
| PubChemID | 16218912 |
| InChIKey | XFXNNOPUDSFVJE-UHFFFAOYSA-N |
| Smiles | Br.Br.CC1=C(CCN)SC(N)=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| water | 31.91 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight319.06.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.13mL | 15.67mL | 31.34mL |
| 5mM | 0.63mL | 3.13mL | 6.27mL |
| 10mM | 0.31mL | 1.57mL | 3.13mL |
| 50mM | 0.06mL | 0.31mL | 0.63mL |
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