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Tocris/N-Arachidonylglycine/1445/25/25 mg
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4000-520-616
AlternativeNames:NAGly
ChemicalName:N-(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)glycine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
GPR18agonist(EC50=44.5nM).Endogenousanandamide-likecompound.LacksaffinityforCB1receptors(Ki>10μM),VR1receptors(EC50>10μM)andanandamidetransporters(IC50>50μM)butcauseshot-plateanalgesiainmicewhengivenorally,andsuppressestonicinflammatorypain.AlsoendogenousGlyT2inhibitor.
TechnicalData
M.Wt | 361.52 |
Formula | C22H35NO3 |
Storage | Desiccateat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 179113-91-8 |
PubChemID | 5283389 |
InChIKey | YLEARPUNMCCKMP-DOFZRALJSA-N |
Smiles | O=C(NCC(O)=O)CCCC=C/CC=C/C/C=CC/C=CCCCCC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
ethanol | 36.15 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight361.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.77mL | 13.83mL | 27.66mL |
5mM | 0.55mL | 2.77mL | 5.53mL |
10mM | 0.28mL | 1.38mL | 2.77mL |
50mM | 0.06mL | 0.28mL | 0.55mL |
MolarityCalculator
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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