Tocris试剂采购 Tocris Bioscience试剂产品信息,Tocris/G-36/4759/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/G-36/4759/10/10 mg

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Tocris Bioscience

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4759/10

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4000-520-616

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Description:SelectiveGPERantagoNIST

ChemicalName:(±)-(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AntagonistofGPER;selectivelyinhibitsestrogen-mediatedactivationofPI3-KbyGPER,butnotbyERα.Alsoinhibitsestrogen-mediatedcalciummobilization(IC₅₀=112nM).StructuralanalogofG-1(Cat.No.3577).

TechnicalData

M.Wt	412.33
Formula	C₂₂H₂₂BrNO₂
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	1392487-51-2
PubChemID	73755224
InChIKey	QTOCPACSSHFGOY-ZCCHDVMBSA-N
Smiles	BrC1=CC4=C(OCO4)C=[C@@]1[C@@H]2NC(C=CC(C(C)C)=C5)=C5[C@@]3([H])[C@@]([H])2CC=C3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	41.23	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight412.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.43mL	12.13mL	24.25mL
5mM	0.49mL	2.43mL	4.85mL
10mM	0.24mL	1.21mL	2.43mL
50mM	0.05mL	0.24mL	0.49mL

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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