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Tocris/GSK 2033/5694/10/10 mg
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Description:PotentLXRantagoNIST
ChemicalName:2,4,6-Trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentLXRantagonist(pIC50=7.5).EnhancesT-cellproliferationandblocksT0901317-antiproliferativeactivityonT-cells.Cellpermeable.
TechnicalData
M.Wt | 591.66 |
Formula | C29H28F3NO5S |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 1221277-90-2 |
PubChemID | 46203250 |
InChIKey | PSOXOVKYGWBTPB-UHFFFAOYSA-N |
Smiles | CC1=CC(C)=CC(C)=C1S(N(CC2=CC=C(C(F)(F)F)O2)CC(C=C3)=CC=C3C4=CC(S(C)(=O)=O)=CC=C4)(=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 11.83 | 20 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight591.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.69mL | 8.45mL | 16.9mL |
5mM | 0.34mL | 1.69mL | 3.38mL |
10mM | 0.17mL | 0.85mL | 1.69mL |
50mM | 0.03mL | 0.17mL | 0.34mL |
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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