Tocris中国采购 Tocris离子通道调控剂,Tocris/GSK 2033/5694/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/GSK 2033/5694/50/50 mg

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Tocris Bioscience

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5694/50

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Description:PotentLXRantagoNIST

ChemicalName:2,4,6-Trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentLXRantagonist(pIC₅₀=7.5).EnhancesT-cellproliferationandblocksT0901317-antiproliferativeactivityonT-cells.Cellpermeable.

TechnicalData

M.Wt	591.66
Formula	C₂₉H₂₈F₃NO₅S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	1221277-90-2
PubChemID	46203250
InChIKey	PSOXOVKYGWBTPB-UHFFFAOYSA-N
Smiles	CC1=CC(C)=CC(C)=C1S(N(CC2=CC=C(C(F)(F)F)O2)CC(C=C3)=CC=C3C4=CC(S(C)(=O)=O)=CC=C4)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	11.83	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight591.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.69mL	8.45mL	16.9mL
5mM	0.34mL	1.69mL	3.38mL
10mM	0.17mL	0.85mL	1.69mL
50mM	0.03mL	0.17mL	0.34mL

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