BiologicalActivity
Highaffinity,water-solubleCB1/CB2receptoragonist(Kivaluesare1.5and0.32nMforCB1andCB2receptorsrespectively).Activeinvivofollowingi.v.andi.c.v.administration.
LicensingInformation
SoldunderlicensefromVCU-IPF
TechnicalData
| M.Wt | 445.04 |
| Formula | C26H36N2O2.HCl |
| Storage | Storeat-20°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 874745-43-4 |
| PubChemID | 24848973 |
| InChIKey | LSHUCXYFAOTXLT-MUCZFFFMSA-N |
| Smiles | OC1=CC(C(C)(C)CCCCN4C=CN=C4)=CC3=[C@@]1[C@H]2[C@H]([C@@](C)(C)O3)CC=C(C)C2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| ethanol | 44.5 | 100 | |
| water | 8.9 | 20mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight445.04.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.25mL | 11.23mL | 22.47mL |
| 5mM | 0.45mL | 2.25mL | 4.49mL |
| 10mM | 0.22mL | 1.12mL | 2.25mL |
| 50mM | 0.04mL | 0.22mL | 0.45mL |
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