生命科学Tocris价格优惠 TOCRIS 4372-10MG,Tocris/IP7e/5699/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/IP7e/5699/10/10 mg

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Tocris Bioscience

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5699/10

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4000-520-616

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Description:PotentNurr1activator

ChemicalName:6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentNurr1activator(EC₅₀=3.9nM).Delaysonsetandreducesseverityofsymptomsinmicewithexperimentalautoimmuneencephalomyelitis(EAE).AlsosuppressesNF-κBsignaling.Brainpenetrantandorallybioavailable.

TechnicalData

M.Wt	390.43
Formula	C₂₃H₂₂N₂O₄
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	500164-74-9
PubChemID	9908426
InChIKey	YCAACZFPADQMAR-UHFFFAOYSA-N
Smiles	CN1C(C2=CC=C(COCCOC)C=C2)=CC3=C(C(C4=CC=CC=C4)=NO3)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	39.04	100
	ethanol	7.81	20mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight390.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.56mL	12.81mL	25.61mL
5mM	0.51mL	2.56mL	5.12mL
10mM	0.26mL	1.28mL	2.56mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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