BiologicalActivity
Syntheticleptinpeptidefragment.Restrictsweightgainandreducesfoodintakeinfemalemicelackingendogenouslycirculatingactiveleptin.
TechnicalData
| M.Wt | 1560.73 |
| Formula | C64H109N19O24S |
| Sequence | SCSLPQTSGLQKPES (Modifications:Ser-15=C-terminalamide) |
| Storage | Desiccateat-20°C |
| CASNumber | 258276-95-8 |
| PubChemID | 90471193 |
| InChIKey | YEHDWBRMEXDYLT-RDEOYNLOSA-N |
| Smiles | [H]N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1560.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.64mL | 3.2mL | 6.41mL |
| 5mM | 0.13mL | 0.64mL | 1.28mL |
| 10mM | 0.06mL | 0.32mL | 0.64mL |
| 50mM | 0.01mL | 0.06mL | 0.13mL |
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