Tocris多肽 TOCRIS 4372-10MG,Tocris/LY 255283/2208/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/LY 255283/2208/50/50 mg

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Tocris Bioscience

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2208/50

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4000-520-616

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Description:Selective,competitiveBLT₂receptorantagoNIST

ChemicalName:1-[5-Ethyl-2-hydroxy-4-[[6-methyl-6-(1H-tetrazol-5-yl)heptyl]oxy]phenyl]ethanone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selective,competitiveantagonistofBLT₂receptors(IC₅₀valuesare~1and>10μMathumanrecombinantBLT₂andBLT₁receptorsrespectively).InhibitsLTB₄-inducedcontractionoflungparenchyma(pA₂=7.2),andreducesLTB₄-mediatedairwayobstructioninguineapigsfollowingi.v.andoraladministration. .

CompoundLibraries

LY255283isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	360.46
Formula	C₁₉H₂₈N₄O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	117690-79-6
PubChemID	122023
InChIKey	WCGXJPFHTHQNJL-UHFFFAOYSA-N
Smiles	CCC1=C(OCCCCCC(C)(C)C2=NN=NN2)C=C(O)C(=C1)C(C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	36.05	100
	ethanol	9.01	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight360.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.77mL	13.87mL	27.74mL
5mM	0.55mL	2.77mL	5.55mL
10mM	0.28mL	1.39mL	2.77mL
50mM	0.06mL	0.28mL	0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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PreparingStockSolutions

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