Tocris产品促销 TOCRIS 4372-10MG,Tocris/ML 179/4957/10/10 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ML 179/4957/10/10 mg

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Tocris Bioscience

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4957/10

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4000-520-616

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Description:Selectiveliverreceptorhomolog1(LRH1)inverseagoNIST

ChemicalName:3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveliverreceptorhomolog1(LRH1,NR5A2)inverseagonist(IC₅₀=320nMandmaximumefficacyof64%repression).Exhibits>31-foldselectivityoverSF1.

CompoundLibraries

ML179isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	422.44
Formula	C₂₁H₂₅F₃N₄O₂
Storage	Storeat+4°C
Purity	≥99%(HPLC)
PubChemID	45100448
InChIKey	MFABFKUNLDYKGH-UHFFFAOYSA-N
Smiles	O=C(C=C(N3CCN(C4=CC=CC(C(F)(F)F)=C4)CC3)NC2=O)N2C1CCCCC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	21.12	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight422.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.37mL	11.84mL	23.67mL
5mM	0.47mL	2.37mL	4.73mL
10mM	0.24mL	1.18mL	2.37mL
50mM	0.05mL	0.24mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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