Tocris抗体，试剂，血清，细胞 Tocris Bioscience现货代理,Tocris/ONO 1078/3026/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/ONO 1078/3026/50/50 mg

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Tocris Bioscience

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3026/50

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4000-520-616

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Description:SelectiveCysLT₁antagoNIST

AlternativeNames:Pranlukast

ChemicalName:N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4(4-phenylbutoxy)benzamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivecysteinylleukotrienereceptor1(CysLT₁)antagonist(IC₅₀valuesare~4-7and3620nMforCysLT₁andCysLT₂respectively).Inhibitscontractionofairwaysmoothmuscle,microvascularleakageintoairwaysandeosinophilinfiltration.Candecreasesymptomsofbronchialasthma.

TechnicalData

M.Wt	481.5
Formula	C₂₇H₂₃N₅O₄
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	103177-37-3
PubChemID	4887
InChIKey	NBQKINXMPLXUET-UHFFFAOYSA-N
Smiles	O=C2C1=CC=CC(NC(C4=CC=C(OCCCCC5=CC=CC=C5)C=C4)=O)=C1OC(C3=NN=NN3)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	24.07	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight481.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.08mL	10.38mL	20.77mL
5mM	0.42mL	2.08mL	4.15mL
10mM	0.21mL	1.04mL	2.08mL
50mM	0.04mL	0.21mL	0.42mL

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