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Tocris/SID 7969543/3440/10/10 mg
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4000-520-616
Description:Selectivesteroidogenicfactor-1(SF-1,NR5A1)inhibitor
ChemicalName:Ethyl2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Selectivesteroidogenicfactor-1(SF-1,NR5A1)inhibitor(IC50valuesare0.76,>33and>33μMatSF-1,RORαandVP16respectively).InhibitsSF-1-dependentluciferaseexpressioninHEK293Tcellsinvitro(IC50=30nM).
CompoundLibraries
SID7969543isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 452.46 |
Formula | C24H24N2O7 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 868224-64-0 |
PubChemID | 4076092 |
InChIKey | KWMBIIQCLUIHDI-UHFFFAOYSA-N |
Smiles | O=C2C1=CC=CC(OC(C)C(OCC)=O)=C1C=CN2CC(NC3=CC=C(OCCO4)C4=C3)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 45.25 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight452.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.21mL | 11.05mL | 22.1mL |
5mM | 0.44mL | 2.21mL | 4.42mL |
10mM | 0.22mL | 1.11mL | 2.21mL |
50mM | 0.04mL | 0.22mL | 0.44mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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