Tocris厂家直采，平行进口 Tocris Bioscience现货代理,Tocris/SR 9238/5854/50/50 mg,受体,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/SR 9238/5854/50/50 mg

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Tocris Bioscience

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5854/50

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Description:PotentandselectiveLXRinverseagoNIST

ChemicalName:Ethyl5-[[[[3'-(Methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveLXRinverseagonist(IC₅₀valuesare43and214nMforLXRβandLXRα,respectively).SelectivelyinhibitsliverLXRoverperipheralLXR.ExhibitsselectivityforLXRoverapanelof20othernuclearreceptors,includingFXR.Reduceshepaticsteatosisinobesemice.

TechnicalData

M.Wt	595.73
Formula	C₃₁H₃₃NO₇S₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1416153-62-2
PubChemID	71478195
InChIKey	HDZWHJYZJWLTAG-UHFFFAOYSA-N
Smiles	CCOC(C1=CC=C(O1)CN(S(=O)(C2=C(C=C(C=C2C)C)C)=O)CC3=CC=C(C4=CC(S(C)(=O)=O)=CC=C4)C=C3)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	59.57	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight595.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.68mL	8.39mL	16.79mL
5mM	0.34mL	1.68mL	3.36mL
10mM	0.17mL	0.84mL	1.68mL
50mM	0.03mL	0.17mL	0.34mL

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